Generic Glucophage (Glycomet Tablets) - Product InformationPrice per 1 tabletGeneric Glucophage (Glycomet tablets) is used to treat type 2 diabetes mellitus (non-insulin dependent diabetes) in adults, when a special diet and exercise alone does not result in adequate control of blood glucose levels. Generic Glucophage is also used for the treatment of polycystic ovary syndrome.The active ingredient present in Generic Glucophage Tablets is Metformin Hydrochloride.Metformin Hydrochloride is marketed under trade names such as Fortamet, Actoplus Met, Avandamet, Glucophage, Glumetza, Riomet, Glycomet, Exermet XR and Glycomet SR .Glycomet tablets are manufactured by USV Limited in the strengths of 250 mg, 500 mg, 850 mg and 1000 mg.Name of the DrugWe supply original Glycomet tablets manufactured by USV Limited . In our online pharmacy Generic Glucophage is available in strengths of 250 mg, 500 mg, 850 mg and 1000 mg.Manufacturer of Glycomet TabletsUSV Limited Website:www.usvindia.comActive Ingredient present in Glycomet TabletsThe active ingredient present in Glycomet Tablets is Metformin Hydrochloride.Each tablet of Glycomet 500 mg contains 500 mg of Metformin Hydrochloride equivalent IPEach tablet of Glycomet 850 mg contains 850 mg of Metformin Hydrochloride equivalent IPEach tablet of Glycomet 250 mg contains 250 mg of Metformin Hydrochloride equivalent IPEach tablet of Glycomet 1000 mg contains 1000 mg of Metformin Hydrochloride equivalent IPUses of Diabetes Medicine Generic Glucophage (Glycomet Tablets)Glycomet tablets (Generic Glucophage), is used along with diet and exercise, to improve glycaemic control in adults with type 2 diabetes mellitus. Generic Glucophage can be used concomitantly with a sulphonylurea or insulin to improve glycaemic control in adults. Glycomet tablets is used to treat patients 17 years of age and older as either monotherapy or in combination therapy. Besides being a diabetes medicine, Generic Glucophage is also used for the treatment of polycystic ovary syndrome (PCOS).How Does Metformin HCl Work - Generic Glucophage Mechanism of ActionMetformin HCl is a biguanide which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin decreases glucose production in the liver, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.Generic Glucophage Tablets (Metformin Tablets) - DosageMetformin Hydrochloride (normal Immediate Release version) comes as an oral tablet in 250 mg, 500 mg , 850 mg and 1000 mg dosage forms. Generic Glucophage is also available as an Extended Release (XR) or Sustained Release, also called Slow Release (SR) version which is available in strengths of 500 mg and 1000 mg. The recommended adult Oral dosage of Generic Glucophage (Glycomet Tablets) for adults is given below:Adult Dosage (Generic Glucophage tablets):The initial adult dosage of Generic Glucophage tablets (Generic Metformin HCl) is 500 mg given orally, twice a day, taken with meals. The maximum daily dose of Glycomet immediate release is 2550 mg given in three divided doses.Dosage of Metformin HCl Tablets (Generic Glucophage) For the Treatment of Polycystic Ovary Syndrome (PCOS):The normal dose prescribed is Generic Glucophage (Glycomet tablets) 1000 mg twice a day.Please consult your doctor for exact dosage instructions, as dosages are individualized. The above dosages are only a guidelineMetformin HCl Tablets (Glycomet) - ContraindicationsMetformin HCl Tablets (Glycomet) are contraindicated in patients with the following conditions:1.Renal disease or renal dysfunction (serum creatinine levels greater or equal to 1.5 mg/dL [males], or greater or equal to 1.4 mg/dL [females] or abnormal creatinine clearance)2.Patients with a past history of ketoacidosis with or without coma.3.Known hypersensitivity to Metformin Hydrochloride or any inactive ingredient present in Glycomet tablets.4.Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. Diabetic ketoacidosis has to be treated with insulin.5.Administration of Metformin HCl (Glycomet Tablets) should be temporarily stopped in patients undergoing radiologic studies involving intravascular administration of iodinated contrast materials, because use of such products may result in acute alteration of renal function.Metformin HCl (Glycomet Tablets) Side EffectsThe common possible side effects of Metformin HCl tablets (Generic Glucophage) include headache or muscle pain, weakness, gastrointestinal upset, including cramps, mild nausea, vomiting, diarrhea increased flatulence, gas, and stomach pain. The most serious potential side effect of Metformin HCl tablets (Glycomet) use is lactic acidosis; this complication is very rare, and the vast majority of these cases seem to be related to comorbid conditions, such as impaired liver or kidney function, rather than to the Metformin itself.Call your doctor immediately if you have any other serious side effect such as:Feeling short of breath, even with mild exertion;Swelling or rapid weight gain; orFever, chills, body aches, flu symptoms.Metformin HCl (Generic Glucophage) for BodybuildingGeneric Glucophage (Metformin HCl Tablets) increases the body's sensitivity to insulin and in bodybuilding this ensures that the carbohydrates go to muscle tissue and there is no build up of fat.Bodybuilders use Generic Glucophage as an oral form of insulin. Metformin HCl tablets will cause greater glycogen supercompensation during carb-ups as well as lowering blood glucose. You have to take Glycomet tablets (Generic Glucophage) with meals and with water to avoid stomach upset.Bodybuilders in professional bodybuilding like to use Metformin (Generic Glucophage) because it gives them several benefits:Full Muscles and No Fat Storage: Muscles will grow fuller when Generic Glucophage is used with high carbohydrate diets. This happens because all the carbohydrates go to build the muscle tissue and there is no build up of fat.Insulin Receptors: Metformin HCl tablets lower blood glucose levels in type 2 diabetic patients. Generic Glucophage also helps to sensitize skeletal muscle cells for insulin that the body produces.Appetite suppression: Studies have shown that prior administration of Metformin HCl produced a reduction in calorie intake after each of the two doses of Metformin treatment. The 1700 mg metformin dose had the most marked appetite suppressant action. Patients treated with Metformin continued to lose weight throughout the period of treatment.Pumps: Bodybuilders using Metformin claim that this medicine helps to pump up muscles and provide outstanding energy in the gym.Generic Glucophage (Metformin HCl Tablets) Dose for BodybuildersFull muscles can be achieved by bodybuilders if a dose of 500 mg to 1000 mg of Generic Glucophage (Glycomet) is taken within 1 hour after a large carbohydrate meal.You can vary the dosage with the amount of carbohydrates present in the meal, but the dosage should not exceed 1000 mg at a time or a maximum of 1700 mg a day.Please note the fast acting regular version of Generic Glucophage must be taken and at least 100 grams of carbohydrates must be taken for every 500 mg of Metformin HCl Tablets (Glycomet) or else low blood sugar (hypoglycemia) sysmptoms may occur.The most effective dose for bodybuilders is 1700 mg per day in divided doses. For bodybuilders on a moderate carbohydrate diet, the dosage has to be split up and taken only with meals containing carbohydrates. The dosage will have to be skipped with meals containg low to no carbohydrates.Warnings & Precautions When Using Generic Glucophage (Metformin HCl Tablets)Below are the warnings and precautions to be taken when using Generic Glucophage (Metformin HCl Tablets): The risk of lactic acidosis caused by Metformin increases with the degree of renal dysfunction, impairment of creatinine clearance and the patient's age. Patients which have serum keratinize levels above the upper limit of the normal range should not receive Metformin HCl.Because impaired liver function can significantly limit the ability to clear lactate, Metformin should generally be avoided in patients with clinical or laboratory evidence of hepatic disease.Patients should be warned against excessive alcohol intake either acute or chronic when undergoing treatment with Metformin, since alcohol intake potentiates the effect of Metformin on lactate metabolism.Treatment with Metformin should be temporarily discontinued 2 days prior to any intravascular radiocontrast study and not restarted until renal function has normalised.It is advisable to discontinue metformin if stress conditions exist especially if gastrointestinal disturbances are noted or acidosis suspected. Therapy should only be resumed after lactic acidosis and ketoacidosis have been excluded.Impairment of vitamin B12 and folic acid absorption has been seen to occur in some patients. Measurements of serum vitamin B12 and folic acid are advisable on an annual basis for patients receiving long-term therapy.Hypoglycaemia does not normally occur in patients receiving treatment with Metformin alone, but can possibly occur when caloric intake is deficient, when strenuous exercise is not compensated by caloric supplementation, or during simultaneous use with other glucose lowering agents e.g. suphonylureas or ethanol.The response to diabetic medicines such as Metformin HCl should be monitored by periodic measurements of fasting blood glucose and glycosylated haemoglobin levels. During initial dose titration period, fasting glucose measurements can be used to determine therapeutic response but thereafter both glucose and glycosylated haemoglobin should be monitored.Metformin HCl With AlcoholAlcohol is known to potentiate the effect of Metformin HCl on lactate metabolism. Patients should not drink a lot of alcoholic drinks while taking Metformin HCl ta..